SERUM PROTEIN CHANGES IN RABBITS AFTER CHRONIC ADMINISTRATION OF LEAD AND CADMIUM

2008, 9 (1)   p. 141-146

Hristo HRISTEV, Dimo PENKOV, Abdul Hallak, Maria Kirova, Bayko Baykov, Atanas Bliznakov

Abstract

The infl uence of lead (5mg/kg b.w) and cadmium (2mg/kg b.w) after chronic treatment of the rabbits on serum protein is investigated. Signifi cantly raised content of the cholesterol, ASAT and ALAT; hypo-albuminemia and hyperbetaglobulinemia of the background of one hypoproteinemia and low A/G coeffi cient are established. On basis of obtained result can to show degree of liver parenchyma damage and as trial for used the hyperbeta-globulinemia (at chronic treatment with cadmium is stronger markedly) as indicator for delimitation of enteral from parenteral toxication, at that is noted hypergamma-globulinemia.

Keywords

serum proteins, lead, cadmium, transpherase

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